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KMID : 0388320000070030415
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Journal of Korean Academy of Fundamental Nursing
2000 Volume.7 No. 3 p.415 ~ p.428
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Survey on the Side Effects of the Vesicant Chemotherapy
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최은숙/Choi, Eun Sook
김금순/주명순/김복자/Kim, Keum Soon/Joo, Myung Soon/Kim, Bok Ja
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Abstract
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The purpose of this study was to identify side effects of the vesicant chemotherapy.
The study was designed to be a descriptive survey. The subjects of this study were 88 patients with various types of cancer, primary lung cancer(25.0%). Advanced gastric cancer(25.0%), breast cancer(20.5%), etc± The mean age was 44.8 years old(range: 16-68).
The questionnaire was completed by nurses of the outpatient unit and chemotherapy ward, and intravenous nurse specialist.
The results of the study were as follows:
1) Chemotherapy was administered with a 23G scalp needle and 24G insyte. Injection site was dorsum of hands (64.7%), cephalic vein(19.3%). Successful rate for the first attempt was 88.6%. The first & second cycle chemotherapy was 29.5% each.. Mainly used drugs were Navelbine(34.1%) , Adriamycin (20. 5%) .
2) Venous problems after chemotherapy were pain(13.6%) incurred by venous, mainly due to the administration of Navelbine: redness at the inravenous site(12.5%) and itching sense 2.3%. Non-venous problems were nausea (18.2%), dullness(14.8%), vomiting(8.0%), facial flushing (6. 8% ) , anxiety (5.7%). Subjective discomforts after chemotherapy were generalized arm pain at the injection side (14.8%), dizziness(6.8%), weakness(5.7%) and general bodyache (5.7%). Systemic anaphylactic reaction and extravasation did not occur.
3) Non-venous problem after chemotherapy were nausea, vomiting & anorexia. Frequency of chemotherapy related to side effects were itching, facial flushing and nausea(pC rapy related to & vomiting(p< rapy related redness(p< .05) ture related redness(p< .05).
Conclusively, cancer chemotherapy patients have had some venous problem. They need appropriate venous access devices for chemotherapy. And other non-venous problem will be managed appropriately.
Further research was required to identify the rate of venous complication or side effects of vesicant chemotherapy.
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